sumo proteins การใช้

• SUMO proteins are small; most are around 100 amino acids in length and 12 kDa in mass.
• The SIM motif may be needed for PIAS proteins to accurately recognize and interact with other SUMO proteins.
• The SUMO protein is a small ubiquitin-like modifier, which is added to lysly ?-amino groups.
• SUMO proteins are similar to ubiquitin, and SUMOylation is directed by an enzymatic cascade analogous to that involved in ubiquitination.
• One can refer to the GeneRIFs of the SUMO proteins, e . g . human SUMO-1, to find out more.
• SUMO proteins, such as SUMO3, and ubiquitin ( see MIM 191339 ) posttranslationally modify numerous cellular proteins and affect their metabolism and function.
• PIAS3 protein also functions as a SUMO ( small ubiquitin-like modifier )-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates.
• When SUMO protein precursors are first expressed, they first undergo a maturation step in which the four C-terminal amino acids are removed, revealing a di-glycine motif.
• I don't see anything of encyclopedic value that could be salvaged into the main articles on autophagy and SUMO protein . talk ) 09 : 03, 10 January 2011 ( UTC)
• When it was discovered that PIAS proteins did far more than simply inhibit STATs, it was proposed that the PIAS acronym should stand for "'P "'leiotropic "'I "'nteractors "'A "'ssociated with "'S "'UMO based on their association with SUMO proteins.